Missouri voters have denied a Republican-backed congressional map that wound its way through the courts before ultimately ending up on the state's ballot.

Democratic former U.S. Sen. Sherrod Brown has won back a seat on Capitol Hill, defeating incumbent Republican Sen. Jon Husted after a close and expensive battle, according to a race call by the Associated Press.

Democrat James Talarico has won the Senate seat in Texas, according to a race call by the Associated Press.

Democrat Amy Acton beat biotech entrepreneur Vivek Ramaswamy, a Republican backed by President Trump, in a race marked in the final weeks by a Ramaswamy attack ad that drew national criticism.

The candidates tapped into voter frustration with the political status quo and will now look to translate their success into policy wins that push Democrats further to the left.