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A medical transport jet with a child patient, her mother and four others aboard crashed into a Philadelphia neighborhood shortly after takeoff, exploding in a fireball that engulfed several homes.

"Significant damage is likely and the disaster is potentially widespread," the United States Geological Survey says.

The Justice Department on Tuesday asked a federal appeals court to throw out the seditious conspiracy convictions of Proud Boys and Oath Keepers leaders, for their role in the Jan. 6, 2021, U.S. Capitol attack.

A new NPR/PBS NewsHour/Marist poll finds the majority of Americans oppose the president's national emergency declaration, don't believe there is an emergency and believe Trump's misusing his power.

The deal signals the end of independence for a once-iconic U.S. company. Tokyo-based Fujifilm said it will cut 10,000 jobs as part of the restructuring of its 56-year-old joint venture with Xerox.

The shooting set off a manhunt that ended when the suspected gunman killed himself as police were closing in on him. Three people were also injured.

A new study by researchers at Brigham and Women's Hospital finds that women and people of Asian descent are the most at risk and that shellfish is the most common allergen.

Get friendly with community leaders; be prepared to be judged by others. Disease detectives from California and Liberia share their best insights.

The former law professor's name came up a number or times during the Jan. 6 investigation committee's hearing on Trump's pressure to get his vice president to overturn the 2020 election.

The IRS is cutting more than 6,000 jobs this week, as part of the Trump administration's downsizing of the overall federal workforce. The job cuts at the IRS come in the middle of the tax-filing season.